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Biological Pathway for schizophrenia risk. Numerous proteins encoded by genes that map to genome-wide association study (GWAS) schizophrenia loci (red font), function in an environmentally responsive pathway with EGR3. Dysfunction in any gene in the pathway may disrupt the normal neurobiological response to stress, resulting in pathology that may give rise to symptoms of Schizophrenia. (PMID: 29520222)
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